
Because true health starts at the root cause.
Whether your focus is aesthetic, regenerative, or preventive-optimizing, our work always begins with a comprehensive diagnosis. It’s the key to personalized therapy and long-term health – supported by the latest technology.
This includes radiation-free transalveolar ultrasound diagnostics (CaviTAU®), which allow us to detect chronic inflammation, silent infections, or degenerative jawbone changes, as well as high-resolution 3D imaging (CBCT) that we later analyze with AI-powered tools.Toxicity testing of root-filled teeth, old fillings, or implants, along with personalized blood and saliva analyses, completes our in-depth diagnostic offering. After all, only those who truly understand what they are dealing with can respond in the best and most individualized way. Carefully, expertly, and always with the human being at the center. It’s no coincidence that our shared journey begins with a detailed conversation.
Book your appointment now and take the first step toward lasting health.

2D X-ray: precise diagnostics with minimal radiation exposure
In integrative biological dentistry, we use low-radiation 2D X-ray imaging for accurate and gentle diagnostics. Depending on the need, we utilize different imaging techniques:
- Bitewing & periapical X-rays – For precise cavity detection and evaluation of fillings and crowns
- OPG / panoramic X-rays – Providing a comprehensive view of teeth, jaw, and bone structure
Although 2D X-rays provide valuable diagnostic insights, they have limitations in detailed diagnostics, as certain issues—such as fine bone defects, hidden inflammations, or three-dimensional structures—cannot be adequately visualized. Nevertheless, this imaging technique helps with the early detection of cavities, bone loss, periodontitis, and larger inflammations. It is also used to monitor implant healing and to determine the need for further diagnostics, such as 3D X-ray or CaviTAU®, if more detailed examinations are required.
Precise 3D diagnostics with low-radiation CBCT imaging: state-of-the-art imaging for highly accurate and safe diagnostics
In integrative biological dentistry, we utilize high-precision 3D CBCT (Cone Beam Computed Tomography) to detect even the smallest changes in the jaw area—while significantly reducing radiation exposure compared to conventional CT scans.
This technology provides exceptionally detailed imaging while remaining relatively low in radiation, making it a safe and effective alternative for precise diagnostics.
Advantages of 3D diagnostics with CBCT:
- Early detection of even the smallest hidden inflammations at the root tips and periodontal structures
- Identification of areas with reduced bone density, such as FDOJ/NICO
- Detailed visualization of the sinuses to assess pathological changes
- Accurate imaging of critical anatomical structures, such as nerves and blood vessels
- Precise measurement for planning complex surgical procedures, including implants and wisdom tooth extractions
The 3D CBCT technology enables a far more detailed diagnosis than conventional 2D X-rays, offering greater safety and better planning for dental and surgical procedures.
Maximum precision with minimal radiation exposure
With cutting-edge 3D imaging, we can identify diagnoses earlier and more accurately, assess potential risks more effectively, and plan surgical procedures with greater precision—ensuring gentle, safe, and sustainable dentistry.
Do you have questions about 3D diagnostics? Contact us — we are happy to assist you!
AI-assisted X-ray diagnostics with Diagnocat
In integrative biological dentistry, we utilize the latest technologies to ensure precise and well-founded diagnostics. With Diagnocat, an AI-powered analysis tool for 2D and 3D X-ray images (CBCT), we receive additional objective support that complements – but never replaces – our professional expertise.
Why do we use AI in X-ray diagnostics?
- Enhanced detection of subtle changes – AI identifies even the smallest inflammations, bone defects, or degenerative processes that require further examination.
- Additional security through objective analysis – Diagnocat systematically highlights abnormalities, but final evaluations always rely on our professional dental expertise.
- Optimized diagnostics & treatment planning – AI provides valuable additional insights, which we interpret individually and integrate into a holistic diagnostic approach.
We use Diagnocat exclusively as a supportive tool to complement our professional diagnostic process – never as the sole basis for decision-making. The final assessment is always conducted by our experienced team, considering all clinical and diagnostic factors.
Book an appointment now & experience cutting-edge diagnostics!
Your data is processed securely and always anonymized.

CaviTAU® – radiation-free bone density measurement with ultrasound in integrative-biological dentistry: precise and gentle diagnostics for a sustainable treatment decision
In integrative biological dentistry, we use the latest radiation-free diagnostic methods to precisely measure bone density and jawbone vitality. CaviTAU®, developed by Dr. Johann Lechner, utilizes ultrasound technology to detect inflammatory or degenerative changes in the jawbone that often remain unnoticed in conventional X-rays.
Pioneers of the CaviTAU® technology
As the originators of this technology, we have the world’s most extensive experience in applying and interpreting CaviTAU® findings. We have published numerous scientific studies demonstrating the link between fatty degenerative osteonecrosis of the jawbone (FDOK + NICO) and systemic diseases. Our research contributes significantly to advancing scientific understanding, enabling precise diagnostics and targeted therapies.
Why is CaviTAU® so valuable?
Conventional 2D and 3D X-rays primarily visualize hard bone structures but do not detect changes in bone density or blood circulation. CaviTAU® directly measures bone quality and vitality, allowing for the early detection of inflammatory processes, fatty degenerations (FDOK + NICO), and areas with poor blood circulation in the jawbone.
Applications of CaviTAU®:
- Measurement of jawbone density – for precise assessment of bone quality.
- Detection of fatty degenerative osteonecrosis (FDOK + NICO/jaw osteitis).
- Identification of necrotic, poorly perfused, or degenerated jawbone areas – especially in cases of unexplained symptoms with no abnormal X-ray findings.
- Early detection of inflammatory processes – around root tips, in gum pockets, and around insufficiently healed implants.
- Assessment of bone quality – to support sustainable implant planning.
CaviTAU® as an integral part of an integrative diagnostic approach
In combination with 2D and 3D X-ray imaging, CaviTAU® enables differentiated and comprehensive diagnostics. While X-rays provide an overview of bone structures, CaviTAU® assesses bone density and degeneration levels.
This combined approach ensures optimal diagnostic accuracy for safe and sustainable treatment decisions in integrative biological dentistry.
We strictly follow the ALARA principle (“As Low As Reasonably Achievable”) to minimize radiation exposure for our patients while maintaining high diagnostic precision.
Maximum diagnostic security for sustainable dentistry
By integrating CaviTAU®, 2D, and 3D X-ray imaging, we can detect hidden inflammatory and degenerative processes in the jawbone at an early stage, provide targeted treatment, and promote long-term oral health – for gentle, precise, and sustainable dentistry.
Do You Have Questions About CaviTAU® Diagnostics?Contact us – we are happy to advise you.
Our Scientific Research on CaviTAU® and Jawbone Inflammation:
- RANTES and fibroblast growth factor 2 in jawbone cavitations: triggers for systemic disease? (Lechner & von Baehr, Int. J. Gen. Med., 2013). DOI: 10.2147/IJGM.S43852
- Chemokine RANTES/CCL5 as an unknown link between wound healing in the jawbone and systemic disease (Lechner & von Baehr, EPMA J., 2015). DOI: 10.1186/s13167-015-0032-4
- Aseptic-avascular osteonecrosis: local “silent inflammation” in the jawbone and RANTES/CCL5 overexpression (Lechner, Schüett, & von Baehr, Clin. Cosmet. Investig. Dent., 2017). DOI: 10.2147/CCIDE.S132691
- Osteoimmunology of TNF-α, IL-6, and RANTES/CCL5: inflammatory patterns in osteonecrosis (Lechner, Rudi, & von Baehr, Clin. Cosmet. Investig. Dent., 2018). DOI: 10.2147/CCIDE.S164631
- Titanium implants and silent inflammation in jawbone – a critical interplay of titanium particles and cytokines TNF-α and RANTES/CCL5 (Lechner, Noumbissi, & von Baehr, EPMA J., 2018). DOI: 10.1007/s13167-018-0135-3
- Ultrasound sonography to detect focal osteoporotic jawbone marrow defects – clinical study with Hounsfield units and RANTES/CCL5 expression (Lechner, Zimmermann, Schmidt, & von Baehr, Clin. Cosmet. Investig. Dent., 2020). DOI: 10.2147/CCIDE.S257227
- Undetected jawbone marrow defects as inflammatory pathways: RANTES/CCL5 as a link to systemic interactions (Lechner, Schmidt, von Baehr, & Schick, J. Inflamm. Res., 2021). DOI: 10.2147/JIR.S311987
- Jawbone Cavitation Expressed RANTES/CCL5: Case Studies Linking Silent Inflammation in the Jawbone with Breast Cancer (Lechner, Schulz, Lejeune, & von Baehr, Breast Cancer (Dove Med. Press), 2021). DOI: 10.2147/BCTT.S311987
- Is preexisting inflamed jaw marrow a “hidden” co-morbidity affecting COVID-19 outcomes? (Lechner, McMahon, Bouquot, Notter, & Schick, Int. J. Immunopathol. Pharmacol., 2024). DOI: 10.1177/03946320241265265
- Upper premolars undergo programmed socket collapse after extraction, leading to cavitations instead of full healing: A radiological study (Ghanaati, Śmieszek-Wilczewska, Al-Maawi, Heselich, & Sader, Bioengineering, 2025). DOI: 10.3390/bioengineering12010001
- Validation of trans-alveolar ultrasound for jawbone density measurement in 210 participants (Lechner, Zimmermann, & Schmidt, Ultrasound Med. Biol., 2021). DOI: 10.1016/j.ultrasmedbio.2021.01.001
- Comparison of cytokine RANTES/CCL5 inflammation in apical periodontitis and jawbone cavitations – Retrospective clinical study (Vasconcelos E Cruz, Notter, Schick, & Lechner, J Inflamm Res., 2024). DOI: 10.2147/JIR.S442693

Immunological blood analysis in integrative-biological dentistry
In integrative-biological dentistry, immunological blood analysis plays a decisive role in the early detection of inflammatory processes and material incompatibilities. This enables targeted, biocompatible therapy and helps to avoid silent inflammation or systemic stress caused by incompatible materials.
What is the lymphocyte transformation test (LTT)?
The LTT is a specialised blood test that detects delayed immune reactions (type IV sensitisation) to dental materials. While immediate reactions (type I allergies) are detected by skin tests, the LTT can also detect delayed allergic reactions that only occur after days or weeks.
In this test, the patient’s white blood cells (lymphocytes) are brought into contact with specific substances such as metals, plastics or dental materials in the laboratory. If sensitisation is present, the lymphocytes react with increased growth – an indication of immunological intolerance.
Why is the LTT important?
- Recognises material incompatibilities at an early stage, before complaints arise.
- Avoids allergic reactions & chronic inflammation that can be triggered by incompatible materials.
- Supports the selection of biocompatible materials to ensure long-term compatibility of dentures and implants.
LTT for dental materials (Dental Check)
The LTT-Dental Check examines whether the body reacts to frequently used dental materials such as plastics, metals or ceramics with an immune response. This is particularly relevant for patients with unexplained complaints following dental treatment, as immunological intolerances can have long-term effects on general well-being.
Areas of application:
- Test for sensitisation to fillings, crowns, bridges and dentures
- Identification of dental materials that are harmful to the immune system
- Support in the selection of compatible alternatives
LTT for plastics
Many dental materials contain plastics that can potentially cause allergic reactions. One well-known example is bisphenol A (BPA), a plasticiser that is found in some plastics and can have hormone-like effects on the body. The LTT for plastics helps to detect intolerances to these substances in order to avoid possible allergic reactions or chronic inflammation.
Areas of application:
- Testing the compatibility of resin fillings, dentures and composite materials
- Identification of allergic reactions to BPA or methacrylates
- Selection of safe alternatives for sensitive patients
LTT for metals
Metals are often used in dental prostheses, crowns or bridges, but in some cases they can trigger allergic reactions or immunological sensitisation. Nickel, palladium, copper, chromium, gold and silver are particularly common triggers.
Areas of application:
- Testing the immune response to dental metals in bridges, crowns or fillings
- Identification of metals that could burden the immune system in the long term
- Ensuring a metal-free or metal-compatible dental restoration
Titanium stimulation test – Compatibility of titanium implants
Titanium is considered biocompatible, but some patients react to titanium implants with immune activation or inflammatory reactions. The titanium stimulation test checks the individual tolerance of titanium and provides information on whether the immune system reacts to dissolved titanium particles.
Areas of application:
- Testing for incompatibility of titanium implants
- Early detection of inflammatory reactions to dissolved titanium particles
- Prevention of implant failure through customised material selection
Note: In addition to the immunological reaction to titanium itself, numerous studies have described titanium oxide microparticles as potentially toxic. These particles can cause oxidative stress and cell damage, but this toxic effect cannot be measured directly on the patient. Nevertheless, this should be taken into account when selecting implant materials.
For this reason, we rely exclusively on all-ceramic implants with a Clean Implant-certified surface to ensure maximum biocompatibility and safety.
RANTES/CCL5: Inflammatory marker for chronic jaw inflammation (FDOK & NICO)
The chemokine RANTES/CCL5 plays a central role in regulating chronic inflammatory processes in the jawbone and can be used as a marker for silent inflammations in areas of poorly healed wounds following jaw surgeries or tooth extractions. Particularly affected are regions where:
- Teeth/wisdom teeth have been removed, but bone healing remains incomplete.
- Implants have been placed, but an unnoticed chronic inflammation in the jaw has developed.
- Root canal-treated teeth or necrotic tissue in the jaw serve as silent inflammation sites.
These inflammatory-degenerative processes in the jawbone (FDOK & NICO) are often caused by osteolytic activity, poor blood circulation, and persistent immune activation. The affected areas frequently appear radiologically inconspicuous but can be identified through increased RANTES/CCL5 expression.
Why is RANTES/CCL5 measurement important?
- Early detection of poorly healed wounds after tooth extractions or jaw surgeries.
- Identification of chronic inflammation around implants, which may lead to long-term bone loss.
- Detection of silent inflammations in root canal-treated or necrotic teeth.
- Recognition of inflamed jawbone areas (FDOK & NICO) as a potential chronic burden on the immune system.
Chronically elevated RANTES/CCL5 levels have been associated in numerous studies with systemic diseases, including neurological disorders, allergies, cancer, autoimmune reactions, mitochondrial dysfunction, and cardiovascular problems. Early diagnosis and targeted treatment of these jaw inflammations can play a crucial role in integrative health.
Sensitization to mercaptans & thioethers (dental toxins)
In integrative biological dentistry, the immune response to toxic sulfur-hydrogen compounds such as mercaptans and thioethers plays a crucial role.
These substances are degradation byproducts found in root canal-treated/dead teeth, necrotic tissue, or chronic jaw infections and can burden the immune system, mitochondrial function, and cellular health.
A blood test for sensitization to mercaptans and thioethers helps detect immune reactions early and take targeted action.
Why is this test important?
Chronic exposure to these toxic compounds can silently promote inflammation and weaken the body’s defense mechanisms. Mitochondria, the energy centers of our cells, are particularly affected. Prolonged exposure can lead to oxidative stress, cellular damage, and an increased susceptibility to chronic diseases, including tumors.
Possible consequences:
- Chronic inflammation in the jaw and other tissues
- ✔ Mitochondrial dysfunction, energy deficiency & cellular stress
- ✔ Weakening of the immune system due to persistent toxin exposure
- ✔ Increased cellular burden, raising the risk of tumors and cancer
- ✔ Contribution to or worsening of chronic diseases, including: Mitochondriopathies, Autoimmune diseases, Rheumatic conditions, Chronic fatigue syndrome (CFS), Fibromyalgia, Neurological symptoms
How does the testing work?
The blood test detects specific immune sensitizations to mercaptans and thioethers, allowing for a precise evaluation of:
- Whether a toxic burden is present
- Whether an immune reaction to these substances exists
- Whether mitochondrial function and cellular health are impaired
- How a personalized detoxification therapy can be designed
Holistic diagnostics & therapy
If sensitization is detected, this may indicate a systemic burden due to chronic jaw infections. In integrative biological dentistry, we focus on gentle, immunologically adapted treatments to relieve the body, protect mitochondria, and reduce the risk of chronic diseases.

Regulation screening / immune status: TH1/TH2/TH17 balance
The cytokine panel assesses immune competence and individual TH1/TH2/TH17 balance. It includes IL-2, IL-4, IL-10, IL-17, and IFN-γ, providing a precise analysis of immune responses to detect chronic inflammation and imbalances at an early stage.
TH1/TH2/TH17 profile – Immune status in integrative-biological dentistry
This diagnostic tool offers valuable insights into immune balance and potential inflammatory dysregulation. It supports targeted treatment—especially in cases of chronic inflammation, periodontitis, or implant intolerance.
TH1, TH2 & TH17 – Understanding immune balance
- TH1 cells: Promote the cellular immune response against viruses & bacteria.
- TH2 cells: Regulate the humoral immune defense, essential for allergies & parasite defense.
- TH17 cells: Support mucosal immunity and are involved in chronic inflammation.
Why is the TH1/TH2/TH17 balance important?
- TH1 dominance: Excessive inflammation, autoimmune reactions
- TH2 dominance: Allergies, immune weakness
- TH17 overactivity: Chronic inflammation, tissue degradation (e.g., periodontitis, peri-implantitis)
Chronic infections as a key factor
Undetected chronic inflammatory sites in the jaw—such as necrotic teeth, FDOK (fatty-degenerative osteolysis), periodontitis, or peri-implantitis—can disrupt TH1/TH2/TH17 balance and contribute to systemic health issues.
Personalized Treatment Planning to Support the Body
Cytokine analysis helps to understand immune responses and determine treatment intensity, ensuring the body is relieved rather than burdened, optimizing its ability to heal.
Targeted immune analysis for better oral health
- Individual assessment of immune responses
- Early detection of chronic inflammation
- Optimization of material compatibility
- Tailored therapies to prevent overburdening the body
Book an appointment now & analyze your immune status!

OroTox® – Rapid test for detecting toxins in dead and root-canal treated teeth
Hidden dental infections and root-treated teeth can release toxins that burden the entire body. The OroTox® test provides a fast and painless way to detect these toxic exposures within minutes, directly in the practice.
How does the OroTox® test work?
- Painless & quick – only a few drops of saliva from the gum pockets are needed
- Immediate results – real-time analysis in the practice
- Detection of toxic metabolic byproducts from bacteria in root-treated or inflamed teeth
Why is a dental toxin analysis important?
Toxins such as thioethers and mercaptans can weaken the immune system, promote chronic inflammation, and be linked to systemic diseases. The OroTox® test helps identify hidden interference fields early and enables targeted treatment.
Check your dental health – for a toxin-free smile and a strong immune system!

Multi-element analysis: Precise compatibility testing for dental materials
In integrative biological dentistry, the compatibility of materials already present in the mouth is crucial. Our multi-element analysis examines fillings, crowns, bridges, and implants for potential material release and their effects on the body.
Why is this analysis important?
Many dental materials contain metals or chemical compounds that may cause intolerances or toxic burdens. Our analysis helps to:
- Identify material release (e.g., heavy metals) in saliva
- Detect individual intolerances early
- Assess systemic burdens caused by metals or plastics
- Select biocompatible alternatives
Our services:
- Material Analysis: Examination of existing restorations for ion or particle release
- Biological Compatibility Testing: Assessment of immune reactions & toxicological effects
- Holistic Evaluation: Personalized treatment recommendations for safer material choices
Test your dental materials for compatibility – for your long-term health!
Book an appointment now & get your saliva analysis done!

Postoperative tissue analysis: diagnosis confirmation & individual burden assessment
The analysis of the extracted diseased tissue is an essential step in confirming the initial diagnosis and precisely assessing individual burdens. Through histological and immunological examination, we obtain valuable insights into the degree of inflammation, toxic burdens, and regenerative potential, allowing for a targeted therapy adjustment.
Confirmation of the initial diagnosis through histological examination
- Verification of the preliminary diagnosis through microscopic analysis of the diseased tissue
- Identification of inflammatory, degenerative, or infectious changes
- Differentiation between chronic and acute inflammatory processes
- Classification of tissue type and exclusion of malignant transformation
Individual burden assessment through advanced analyses
- RANTES/CCL5 cytokine quantification to measure inflammatory pathways and immune responses
- Toxicological analysis for heavy metals or material-induced burdens
- Evaluation of tissue regeneration to assess healing potential
Systemic interpretation & therapy optimization
- Correlation of findings with existing diagnoses for a more precise, individualized therapy plan
- Identification of burdens that may affect the healing process
- Foundation for tailored, holistic follow-up care
Expert analysis by our specialized partners
For the detailed histological and immunological evaluation of extracted tissue samples, we collaborate with leading experts:
- PD Dr Katharina Schmidt – Pathology Straubing
- IMD Berlin – Institute for Medical Diagnostics
These specialized laboratories provide precise results, enabling targeted therapy adjustments and sustainable regeneration.

Individualized treatment planning: Integrative care for your health
In our integrative biological dentistry, we focus on individualized treatment planning that centers on your unique biological conditions. Along with thorough clinical findings and imaging studies, we incorporate results from blood tests, immune status evaluations, and intolerance tests into the planning process. We understand that systemic diseases can influence oral health, and conversely, oral conditions can have an impact on the entire body. We consider these interconnections to ensure an integrative approach to treatment.
Through comprehensive diagnostics, we develop a tailored treatment plan that supports not only your dental health but also your overall biological system. We combine modern scientific knowledge with natural healing methods to promote sustainable healing and prevention. In this way, we provide treatment that not only protects your teeth but also strengthens your general well-being in the long term.
You will receive a customized plan that we believe will bring out the best possible outcome from your therapy and lead to better health in the long run.
We understand the connections.
Schedule your personal appointment today.